Editor's note: This article has been reviewed and updated for accuracy in 2026. Cannabis-based products have been used for centuries. In fact, the oldest record of cannabis use dates all the way back to 2737 BC, when Shen Nung used the plant as medicine. It was also commonly used in Ancient Greece and Rome for its medicinal properties. Shen Nung: Obviously this guy ripped Fast forward to the 21st century and the use of products that contain cannabinoids for health and wellness is still common; in fact, as people around the world are steering away from manufactured products that are laden with chemicals, cannabis seems to be more popular than ever before. Given the fact that it’s natural and it can treat a broad-range of ailments – from aches and pains to depression and anxiety – it’s easy to see why cannabis use has soared. As scientists today are discovering (like terpenes for exampl